CH4120-0A - Pharmaceutical Chemistry II: Drug Design (Fall 2009)

Focuses on the important concepts in the design and synthesis of drugs. Rational basis for drug design including synthetic, computational and biochemical concepts will be discussed. Topics include structure-activity relationships, synthesis and reaction mechanism, and case studies of drugs.

Credits: 3.0
Lec-Rec-Lab: (3-0-0)

Terms Offered: Fall
Prerequisites: CH 4110
Course Restrictions: May not be enrolled in one of the following Class(es): Freshman
Course Instructor:
  Dr. Dallas K. Bates
620A ChemSci
(906) 487-2059

Course Documents:

01 CH4120 Syllabus Fall 09.pdf
02 Vocabulary for CH4120.pdf
03 Drug Design class notes 1.pdf
04 Drug Design class notes 2.pdf
04a HyperChem Exercise 1 - drawing rotating and rendering.pdf
04b HyperChem Exercise 2 - Geometry optimization and log files.pdf
04c HyperChem Exercise 3- conformational analysis RMS overlay.pdf
04d Figure 3 for HyperChem Exercise 3.doc
05 Random Screening-HTS Assignment.pdf
05a article - Antimalarial Agent Hits Novel Enz.pdf
06a Pharmacophore-based drug design reading assignment.pdf
07 Drug Design by Conformational Searching.pdf
08 HyperChem Exercise for Drug Design by Conformational Searching.pdf
09 Structure based drug design - lecture notes.pdf
10 Structure-based drug design article to read JMC 2007 50 2289.pdf
12 Intro to Protein Kinase Inhibitors and Case Study - Gleevec Iressa.pdf
13 CEN Centering on Chirality.pdf
13 Structure-based drug design - reading assign #2.pdf
14 Class notes to accompany Chirality lectures.pdf
15 Structure-based drug design - reading assign #2.pdf
 
!!More Asymmetric Synthesis Articles to read:
 
levobupivacaine TL 1996 37 6399-6402.pdf
levobupivacaine TL 2004 46 19-21.pdf
 
 
2009 Posters:
 
Alex.pdf
Giri.pdf
Graham.pdf
Jake.pdf
Katrina.pdf
Kelsey.pdf
Nazmiya.pdf
Sissi and Brigitta.pdf
Zhiwei.pdf