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Group News: [02/06] Dr. Thompson published, "Synthesis, Photophysical Effects, and DNA Targeting Properties of Oxazole Yellow-Peptide Bioconjugates" in Bioconjugate Chemistry. [06/06] Dr. Thompson's manuscript entitled, "DNA sequence-directed assembly of two peptide bioconjugates" was accepted for publication in Bioorganic Chemistry. [06/06] Dr. Thompson's manuscript entitled, "Expression, purification and characterization of individual bromodomains from human Polybromo-1" was accepted for publication in Protein Expression and Purification. Research Focus: Our multi-disciplinary research program aims to understand the molecular recognition features and assembly mechanisms of gene regulation. A growing number of studies are finding diverse and essential roles for molecular recognition events in mediating information transfer and complex assembly in biology. In fact, biological outcomes are often due to physical interactions between proteins that are so highly selective that seemingly minor chemical modifications (i.e. methylation, acetylation or phosphorylation) can completely abolish biomolecular recognition processes and redirect signaling pathways. |
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Coursework for Fall 2006: CH1800 - Biochemistry Orientation CH6790 - Protein Chemistry |
Contact: Martin Thompson, Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931-1295, phone: 906.487.3522, fax: 906.487.2061, thompson@mtu.edu |
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